周宗翰

teacher_17 

周宗翰(Chou, Tzung-Han)教授

………………………………………………………………………………………………………………………………………………………………………….

學歷:
國立清華大學化工博士
國立成功大學化工碩士
國立成功大學化工學士

專長:界面科學、藥物釋放載體、生物界面、生醫工程

………………………………………………………………………………………………………………………………………………………………………….

研究室
EC310
分機
4625
實驗室名稱
重點設備
粒徑暨界面電位分析儀、長工作距離螢光顯微鏡、KSV單分子層設備,HPLC、自動取樣機、UV及FL偵測器,高效能DSC、CUP-HORN 超音波震盪器
實驗室
EC418
分機
4688
Mail
教授課程

程序控制 、智慧財產權與工程倫理

網路輔助教學
教師著作
serviceicon1

………………………………………………………………………………………………………………………………………………………………………….

主要研究領域:
藥物劑型設計與製備、生醫材料、熱力學、界面科學、奈米生技化妝品、化妝品載體的製備
與功效性評估

近三年著作及專利:

  1. Tzung-Han Chou (周宗翰)*, Chien-Wen Chen(陳建文), Chia-Hua Liang, Li-Hsien Yeh, Shizhi Qian, “Simple synthesis, self-assembly, and cytotoxicity of novel dimeric cholesterol derivatives.” Colloids and Surfaces B: Biointerfaces, 116, 153-159 (April 2014). (SCI) [2013 Impact factor: 4.287], [Biophysics, 14/74]
  2. Chia-Hua Liang, Li-Hsien Yeh, Pei-Wen Liao, Tzung-Han Chou*, “Characterization and in vitro biocompatibility of catanionic assemblies formed with oppositely charged dicetyl amphiphiles.” Colloids and Surfaces B: Biointerfaces 126, 10-17. (February 2015). (SCI) [2013 Impact factor: 4.287], [Biophysics, 14/74]
  3. Yu-Shen Cheng, Kuan-Yu Chen, and Tzung-Han Chou. “Concurrent calcium peroxide pretreatment and wet storage of water hyacinth for fermentable sugar production.” Bioresource technology 176, 267-272 (January 2015). (SCI) [2013 Impact factor: 5.039], [Biotechnology & Applied microbiology, 17/165]
  4. Zachary Milne, Li-Hsien Yeh, Tzung-Han Chou, Shizhi Qian, “Tunable donnan potential and electrokinetic flow in a biomimetic gated nanochannel with pH-regulated polyelectrolyte brushes.” The Journal of Physical Chemistry C 118, 19806-19813 (August 2014). (SCI) [2013 Impact factor: 4.835], [Materials science, Multidisciplinary, 29/251]
  5. Tzung-Han Chou*, Chia-Hua Liang, Yu-Chieh Lee, Li-Hsien Yeh, “Effects of lipid composition on physicochemical characteristics and cytotoxicity of vesicles composed of cationic and anionic dialkyl lipids.” Physical Chemistry Chemical Physics 16, 1545-1553 (January 2014). (SCI) [2013 Impact factor: 4.198], [Physics, Atomic, Molecular & Chemical, 5/33]
  6. Laura Benson, Li-Hsien Yeh, Tzung-Han Chou, Shizhi Qian, “Field effect regulation of Donnan potential and electrokinetic flow in a functionalized soft nanochannel.” Soft Matter, 9, 9767-9773 (November 2013). (SCI) [2013 Impact factor: 4.151], [Materials science, Multidisciplinary, 33/251]
  7. Chia-Hua Liang, Wen-Yueh Ho, Li-Hsien Yeh, Yu-Shen Cheng, Tzung-Han Chou*, “Effects of 1-hexadecyl-3-methylimidazolium ionic liquids on the physicochemical characteristics and cytotoxicity of phosphatidylcholine vesicles.” Colloids and Surfaces A: Physicochemical and Engineering Aspects, 436, 1083-1091 (September 2013). (SCI) [2013 Impact factor: 2.354], [Chemistry, Physical, 59/136]
  8. Rong-Jyh Lin, Chuan-Min Yen, Tzung-Han Chou, Feng-Yu Chiang, Guey-Horng Wang, Ya-Ping Tseng, Lin Wang, Ting-Wei Huang, Hui-Chuan Wang, Leong-Perng Chan, Hsiou-Yu Ding, Chia-Hua Liang, “Antioxidant, anti-adipocyte differentiation, antitumor activity and anthelmintic activities against Anisakis simplex and Hymenolepis nana of yakuchinone A from Alpinia oxyphylla.” BMC complementary and alternative medicine, 13(1), 237-250 (September, 2013). (SCI) [2013 Impact factor: 1.877], [Integrative & Complementary Medicine, 8/22]
  9. Chia-Hua Liang, Leong-Perng Chan, Tzung-Han Chou, Feng-Yu Chiang,Chuan-Min Yen, Pin-Ju Chen, Hsiou-Yu Ding, Rong-Jyh Lin, “Brazilein from Caesalpinia sappan L. antioxidant inhibits adipocyte differentiation and induces apoptosis through caspase-3 activity and anthelmintic activities against Hymenolepis nana and Anisakis simplex.” Evidence-Based Complementary and Alternative Medicine, 2013, 1-14 (February, 2013). (SCI) [2013 Impact factor: 2.175], [Integrative & Complementary Medicine, 6/22]
  10. Leong-Perng Chan, Tzung-Han Chou, Guey-Horng Wang,Ya-Ping Tseng, Pin-JuChen, Da-Long Cheng, Chia-Hua Liang, “Ugonin K induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal pathway in human skin cancer cells.” Advanced Materials Research, 690, 1422-1425 (May, 2013). (EI)
  11. Chia-Hua Liang, Tzung-Han Chou, Ya-Ping Tseng, Hsiou-Yu Ding, “trans-Caffeic acid stearyl ester from Paeonia suffruticosa inhibits melanin synthesis by cAMP-mediating down-regulation of α-melanocyte-stimulating hormone-stimulated melanogenesis signaling pathway in B16 cells.” Biological and Pharmaceutical Bulletin, 35, 2198-2203 (September, 2012). (SCI) [2013 Impact factor: 1.778] [Pharmacology & Pharmacy, 161/256]
  12. Chia-Hua Liang, Leong-Perng Chan, Hsiou-Yu Ding, Edmund Cheung So, Rong-Jyh Lin, Hui-Min Wang, Ying-Ging Chen, Tzung-Han Chou*, “Free radical scavenging activity of 4-(3,4-dihydroxybenzoyloxymethyl)phenyl-o-β-d-glucopyranoside from Origanum vulgare and its protection against oxidative damage.” Journal of Agricultural and Food Chemistry, 60, 7690-7696 (July, 2012). (SCI) [2013 Impact factor: 3.107], [Agriculture, Multidisciplinary, 2/56]
  13. Chia-Hua Liang, Guey-Horng Wang, Tzung-Han Chou, Shih-Hao Wang, Rong-Jyh Lin, Leong-Perng Chan, Edmund Cheung So, Jyh-Horng Sheu, “5-epi-sinuleptolide induces cell cycle arrest and apoptosis through tumor necrosis factor/mitochondria-mediated caspase signaling pathway in human skin cancer cells.” Biochimica et Biophysica Acta (BBA) – General Subjects, 1820, 1149-1157 (July, 2012). (SCI) [2013 Impact factor: 3.829], [Biophyics, 19/74]
  14. Leong-Perng Chan, Tzung-Han Chou, Hsiou-Yu Ding, Pin-Ru Chen, Feng-Yu Chiang, Po-Lin Kuo, Chia-Hua Liang, “Apigenin induces apoptosis via tumor necrosis factor receptor- and Bcl-2-mediated pathway and enhances susceptibility of head and neck squamous cell carcinoma to 5-fluorouracil and cisplatin.” Biochimica et Biophysica Acta (BBA) – General Subjects, 1820, 1081-1091 (July, 2012). (SCI) [2013 Impact factor: 3.829], [Biophyics, 19/74]
  15. Chien-Hsiang Chang, Chia-Hua Liang, Yu-Ying Hsieh, Tzung-Han Chou*, “Molecular packing and lateral interactions of distearoylphosphatidylcholine with dihexadecyldimethylammonium bromide in langmuir monolayers and vesicles.” Journal of Physical Chemistry B, 116, 2455-2463 (February, 2012) (SCI) [2013 Impact factor: 3.337], [Chemistry, Physical, 39/136]
  16. Tzung-Han Chou*, “Current application of lipid- and surfactant-based vesicles for cosmeceuticals: a review” Current Pharmaceutical Biotechnology, in press, (February, 2015) (SCI) [2013 Impact factor: 2.511], [Pharmacology & Pharmacy, 112/256]
  17. Tzung-Han Chou*, Chien-Wen Chen “Synthesis, self-assembly, and in vitro biocompatibility of a novel steroidal oxime.” Current Pharmaceutical Biotechnology, in press, (September, 2014) (SCI) [2013 Impact factor: 2.511], [Pharmacology & Pharmacy, 112/256]

專書著作:

  1. 周宗翰、張乃方、呂祖尚、陳玉芬、嚴嘉蕙、楊濟華,”界面化學(二版)”,第1章表面張力與界面張力,p1.1-1.13,2013,02,華格那企業有限公司,ISBN 978-986-5929-88-6。
  2. 周宗翰、梁家華, “奈米液胞化妝品的開發與應用”,化工技術,Vol.225,p122-130,(December, 2011),ISSN 1814-9154。

專利:

  1. 丁秀玉、梁家華、周宗翰 , “用於防止黑色素沉澱之沙苑子萃取物”, 中華民國,發明專利,第I477292,民國103(2015)年03月21日。
  2. 丁秀玉、梁家華、周宗翰, “用於防止黑色素沉澱之防風草萃取物”, 中華民國,發明專利,第I474828,民國103(2015)年03月01日。
  3. 周宗翰、梁家華、蕭靖樺, “用於皮膚美白之奈米聚集體及其製造方法”,中華民國,發明專利,第I457140,民國103(2014)年10月21日。
  4. 周宗翰、梁家華、洪偉章, “含有蘆薈羥基蔥?衍生物之微脂粒遞送系統及其製造方法”, 中華民國,發明專利,第I439294,民國103(2014)年6月1日。
  5. 梁家華、周宗翰、丁秀玉 、洪偉章 、陳品儒, “利用吸光值變化定量評估抑制黑色素生成效果之方法” 中華民國,發明專利,第I439691,民國103(2014)年6月1日。
  6. 丁秀玉、梁家華、周宗翰, “牡丹皮萃取物及其製造方法暨其抗氧化之應用”, 中華民國,發明專利,第I433690,民國103(2014)年04月11日。
  7. 丁秀玉、梁家華、周宗翰, “牡丹皮萃取物及其製造方法暨其皮膚美白之應用”, 中華民國,發明專利,第I417127,民國102(2013)年12月01日。
  8. 梁家華、丁秀玉、周宗翰,“來自牛至(Origanum vulgare) 之新化合物及其用途”,中華民國發明專利,第I386232,民國102(2013)年02月21日。
  9. 梁家華、周宗翰、陳亭宇、曾雅萍、易采旋、陳品儒、程達隆, “動物固定裝置”,中華民國新型專利,M 420171,民國101(2012)年01月11日。

三年內曾任主持人執行之計畫:

項次 年度 計畫名稱及編號 補助單位
1 103 奈米結構活性脂質載體之界面性質、製備、及物化特徵(1/2)。
(MOST 103-2221-E-224-077-MY2)
科技部
2 103 D-α-生育酚聚乙二醇1000琥珀酸酯-功能性奈米乳液的開發。
(MOST 103-2622-E-224-005-CC3)
科技部
3 103 103年度中小企業即時技術輔導計畫-農業廢棄物香蕉花之效能評估及乳霜產品之開發。
(103-273-01及103-273-02)
經濟部工業局
4 102 包覆minoxidil活性奈米聚集體的製備與開發。
(NSC102-2622-E-224 -011-CC3)
國科會
5 102 102年度中小企業即時技術輔導計畫-蠶絲蛋白之化妝水、精華液及乳液產品開發。
(102-327-01 及102-327-02)
經濟部工業局
6 101 雙效奈米粒子之開發與應用。
(NSC 101-2622-E-224-010 -CC3)
國科會

其他獲獎事蹟

項次 事蹟
1 指導學生獲得2014馬來西亞國際發明展-金牌
2 指導學生獲得2014波蘭國際發明展-金牌
3 指導學生獲得2013韓國首爾國際發明展-銀牌
4 指導學生獲得2014澳門國際發明展-銅牌
5 指導學生獲得2014台北國際發明暨技術交易展-銅牌
6 指導學生入圍科技部創新創業激勵計畫第21號-活粒旺
7 指導學生獲得101、102、103學年度雲科大化材系實務專題成果展-優等獎
8 指導學生入選103年度中區技專校院創新、創業、商品化-崢嶸棟梁
9 指導學生參加雲科大師生創新園夢計畫-搶先追夢-獲得最具潛力獎
10 協助辦理第32屆台灣觸媒與反應工程研討會
11 協助2014年中華民國界面科學學會年會暨論文發表研討會,受邀演講。
12 協助2013台灣化學工程學會60週年年會暨國科會化工學門成果發表研討會,受邀演講及壁報競賽評審。
13 協助101年度中國工程師學會學生分會工程論文競賽,受邀擔任初、複選審查委員。
14 協助2011國際化粧品科技研討會,受邀演講。
15 協助2013台北國際發明暨技術交易展出(國科會科技創新館區)。
16 2014國立雲林科技大學 研發績優新人獎

………………………………………………………………………………………………………………………………………………………………………….